MECHANISM OF ACTION
SARCLISA Is a
Multimodal Anti-CD38 Monoclonal Antibody
SARCLISA Is a Multimodal Anti-CD38 Monoclonal Antibody
Targeted binding to a specific epitope
induces distinct antitumor activity1-3
Directly destroys
myeloma cells through apoptosis without the need for crosslinking
inhibits
CD38 enzymatic activity
through suppression of the
CD38 ectoenzyme
triggers
cancer cell death through tumor cell targeting, including ADCC, ADCP, and CDC
Enhances
immune cell function through NK cell activation and a decrease in immunosuppressors
Directly destroys
myeloma cells through apoptosis without the need for crosslinking
inhibits
CD38 enzymatic activity
through suppression of the
CD38 ectoenzyme
triggers
cancer cell death through tumor cell targeting, including ADCC, ADCP, and CDC
Enhances
immune cell function through NK cell activation and a decrease in immunosuppressors
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