The median duration of treatment was 41 weeks with SARCLISA + Pd vs 24 weeks with Pd. 1
At a median follow-up time of 11.6 months, 43 patients (27.9%) receiving SARCLISA + Pd and 56 patients (36.6%) receiving Pd had died. Median OS was not reached for either treatment group at interim analysis. The OS results at interim analysis did not reach statistical significance. 1
ORR: SARCLISA + Pd (95% CI: 52.2%, 68.2%), Pd (95% CI: 27.8%, 43.4%). 95% CI estimated using the Clopper-Pearson method.
Median time to first response was 35 days with SARCLISA
+ Pd vs 58 days with Pd alone among responders1
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®)
Isatuximab-irfc (SARCLISA) is the only mAb in combination with pomalidomide and dexamethasone included as an NCCN Guidelines® Category 1 recommended regimen for previously treated multiple myeloma.2